Clay Siegall Leads in Cancer Treatment through ADCETRIS Antibody Drug Conjugate

Genetics study is the exploration of genes, genetic variation as well as hereditary in humans and animals. Genetics research is a field in biology that explores the inheritance of diseases as well as characteristics of living organisms. Researchers and scientists have massively invested in the study of genetics in a bid to find the causative agents of diseases like cancer. Clay Siegall is a good example of one of the many research scientists who has taken the time to study genetic variation with the aim of finding treatment therapies as well as drugs for cancer.




Clay’s career began in college when a relative fell sick, and the chemotherapy session took a toll on the patient. As he describes the series of events in the interview, the family member was in pain. His passion for saving lives developed at that point. Consequently, he began to explore science and biology.


Seattle Genetics


In 1998, Clay established Seattle Genetics with the aim of finding treatment for cancer and other life-threatening ailments. The company is biotech based, and it specializes in the generation of therapeutic drugs. As the chief executive officer of the company, his roles include managing the team of scientist researchers and making decisions on behalf of the management. He is the brain behind all operations in the company. Seattle Genetics focuses on using modern state of the art technology and resources in finding proper and painless treatment for patients.




Recently, the company launched ADCETRIS, a drug antibody conjugate that received the first FDA approval. ADCETRIS has since paved the way for Seattle Genetics to inject a pipe for medicinal products into various markets. As proof that ADCETRIS is a viable treatment option, it has been approved in over fifty countries including Canada. The drug has aided in the development of over twenty drugs in the market with most of them leading to business partnerships between Seattle Genetics and pharmaceutical firms. Through it all, the alumnus of the George Washington University has been the head cheerleader of the company.


Clay’s Profile


Siegall is the chief executive officer of Seattle Genetics. He is dedicated to finding treatment solutions for cancer. He graduated from the University of Maryland with a degree in zoology. He also has a Ph.D. in genetics.


Prevention is Always Better Than Treatment for Diseases

If one would ask anyone whether they would prefer getting treatment for a disease or preventing it from occurring at all, most people would answer that they would rather prevent it. This is one of the reasons that Lifeline Screening was established. This is to give people a chance to look out for any risk factors of diseases so that they could take the necessary steps to avoid them. There are tons of diseases that are actually very hurtful for people that get them. Also, a lot of diseases are fatal once they are contracted. This is why it is important that people get whatever help they can from Lifeline Screening.

One of the professionals of Lifeline Screening is Dr. Andrew Manganaro. He is very passionate about making sure that his patients are able to get the care they need so that they don’t have to undergo treatment for diseases. While it is bad enough to get some of the diseases, it can be even worse for people when they start treatment. After all, a lot of diseases require treatments that mess up the system. Fortunately, if one can avoid the disease, then he is in good shape.

Dr. Andrew Manganaro has gotten the inspiration for Lifeline when he has seen many problems that could’ve been prevented with knowledge of the condition that the patient had. Dr. Manganaro has worked as a cardiovascular surgeon before starting up Lifeline Screening. He does a lot of work with his team in order to bring any ideas he has to reality. He takes a lot of time to make sure that his ideas are helpful to the patients.

With Lifeline, people have a better chance to catch any disease or condition they have before it is too late and it gets to fatal levels.


Adam Milstein Knows how to Win


Adam Milstein is more just a Managing Partner of Hager Pacific Properties. He is a father and husband. He excels in his partnerships and leaderships. He knows the flavor of life. Altogether, he is a man worth taking notes from. With inspiring advice and the fruits of labor to valid his philosophies, the deeds and words of wisdom from this anthropologist have an air of truth with them.


Before his walk across the graduation stage from higher learning, Adam Milstein recalls knowing that the work and rewards he likes to see were to be the results from his very own work habit and education. He also recalls a lesson in growing strength in business practices by building structure through the repeated completion of tasks. That is how he knows to complete a task in business there has to be more than just simple follow through. There has to be absolute push through. Moreover, he knows from years of experience that steady activity is needed to survive fluctuations and flips in his line of business.


Stability and success in real estate requires, follow up, consistency and a persistent nature, according to Adam Milstein. However, there is an aspect to his mindset and operating procedure that some find challenging to master. That is to not set too specific goals. A pit fall he warns against to all entrepreneurs is trying to make it too big too fast and expecting fortunes overnight. He knows that real foundations take time to build.


He knows this because he is Co-founder of the Adam and Gila Milstein Family Foundation. Through this foundation he is able to do some of his very best work by supporting several organizations. Although the range of organizations his foundation supports is wide, they all have one thing in common. They all seek to contribute strength to the Jewish nation, Israel and the United States.


However, his family foundation is not the only organization in which Adam Milstein is a Co-founder. He holds that title with the IAC (Israeli-American Council) where he is the chair of the organization’s expansion. The list of other organizations that have him for aboard member is somewhat extensive to include StandWithUs, Hasbara Fellowships and the AIPAC (American Israel Public Affairs Committee.



How We Use Securus Technologies to Catch Jail Escapees

I work in a jail and on the task force responsible for finding inmates who have escaped. It doesn’t matter the type of inmate that escapes, they all can be very dangerous if they are on the outside and desperate to stay out of jail. As a corrections officer, we can do everything possible to keep the inmates in the jail, but every once in a while the inmate has luck on their side for a very small window and they make the most of it.


The fist thing that I do when I am notified an inmate is out of the jail is to speak with their family. Usually these inmates have no one to turn to except family, so we try to get to them and uncover any evidence that will shed some light on this inmate and their whereabouts. Most time, these families who are protecting their family member will never expose where they are, so we have to take things to another level to get the truth out of the family.


The best resource we have is the Securus Technologies inmate communication system in our jail. Once trained on the LBS software, me and my fellow officers can listen to conversations between inmates and family in a whole new light. We trust the Securus Technologies family and all 1,000 of their employees because their motto is existing to make the world a safer place. Based out of Dallas TX, even the CEO of Securus Technologies, Rick Smith, stands by those words.


The new phone system allowed us to hear chatter between inmates who were making arrangements for the escapee to hide out while the heat died down. Once we were able to piece together the information, we found our suspect hiding out on a deserted farm where friends where bringing him supplies on the word of the inmates still in the jail and talking in code on the phones.


The UAE Exchange Now Adops NuoDB

No other database architecture comes close to the performance of NuoDB. Using the power of cloud computing clusters with NuoDB will allow for unlimited amounts of requests to be queried without lag.

The stability of a large enterprise depends on the stability of their database system. Only NuoDB will effectively keep the database up with its monolithic nature. Once one machine in the cluster shuts down, the rest of the machines will pick up the slack as if nothing had happened.

Migrating over to NuoDB is a breeze considering it is based on SQL database cloud technology. The giants like MySQL and MicrosoftSQL will be compatible with the syntax of NuoDB. The difference is that these databases are entirely inefficient when ran on clusters.

Since being founded in 2008, the company had received over $59.7 million in venture capital funding. They had been a favorite amongst Dassault Systèmes, Hummer Winblad Venture Partners, and much more. Dassault Systèmes even runs NuoDB as their primary cloud database for financial systems.

Kodiak, Alfa Systems, and UAE Exchange have all found success after switching to NuoDB. These companies depend on cloud computing considering the high volume of financial transactions they encounter. Become like these large-scale companies and harness the power of cloud computing.

Trouble Sleeping? Wengie Has You Covered!


Trouble sleeping? Wengie has you covered with 20 ways to help you fall asleep faster. In her Youtube video “How to Fall Asleep FAST! 20 Life Hacks for Sleep Everyone Should Know!!” Wengie goes through some of the most popular tricks to get you to dreamland fast. She starts off discussing the benefits of white noise, then goes on to mention the importance of temperature and other environmental factors such as making the room as dark as possible. She also suggests consuming honey, milk or oatmeal before bed to help get those sleepy time nutrients. Breathing techniques such as the 4-7-8 method and meditation also can help the body to relax before bed. Another important thing she mentions is how helpful it is to be on a set sleep/wake schedule, even suggesting that not only should you have an alarm to wake you up, but also have one set to get you to bed the same time every night.


Another interesting sleep hack that she mentioned was getting the Twilight App for your phone. While it is best to limit use of phones and technology right before bed this app will make it a little easier to fall asleep if you do use it. What it does is it takes the blue light out of your phone which has shown to make it harder for people to fall asleep. Wengie also mentions to try to keep the bed solely for sleeping. To hear all of her wonderful tips check out her Youtube video for yourself.

James Dondero, The Pharoah

When someone mentions James Dondero, they have to mention his accomplishments. For years, he held high-ranking positions at numerous companies. Moreover, Dondero has proven himself as an asset to all. With decades of expertise, it remains easy to see why James Dondero remains the man he is today. Furthermore, Dondero remains the president of Highland Capital. Also, he remains the Co-founder of the company. In addition, he lives in Dallas, TX.


For over 3 decades, James Dondero effortlessly climbed the ladder of success. Moreover, he has specialized in credit and equity markets. Moreover, he has focused his efforts on high-yield and distressed investing. For those unaware, Highland Capital remains a leader in developing the Collateralized Loan Obligation market. Furthermore, they develop credit-focused solutions for institutional and retail investors globally. In addition, the company remains renowned for their high-quality goods and services. To name a few, their products include separate institutional accounts, CLOs, hedge funds, private equity funds, mutual funds, REITs, ETFs and so forth.


Due to such notoriety, the company has received numerous awards for their offerings. Aside from being the president of Highland Capital Management, James Dondero also remains the chairman of Cornerstone Healthcare, CCS Medial, Nexbank, and so forth. Furthermore, he serves as a board member of American Banknote and MGM Studios. In spite of having such a plethora of positions to uphold, James Dondero remains a poignant philanthropist. Giving back to the community is something he values dearly. In any way he cans, James Dondero selflessly gives back to communities in the areas that matter most.


To name a few, Dondero has generated generously in the areas of education, veteran’s affairs, and public policy. Before his ascendancy at Highland Captial, James Dondero helped create the GIC subsidiary of Protective Life. As a result, the company witnessed an economic boom. To be exact, the company saw $2 billion dollars between 1983 and 1993. Aside from being a success story, James Dondero’s rise to the top did not happen overnight. In addition, Dondero holds numerous degrees under his belt. To this day, James Dondreo sets the standard in his industry.

The Technical Artist: Eric Pulier

Eric Pulier was born in New Jersey and went to school Harvard University and attended some classes at MIT. Pulier is better known for being a philanthropist, author, technologist and entrepreneur.

Pulier is well versed in service-oriented architecture, or SOA. SOA is a collection of services that communicate with one another. Cloud computing is one more modern and common way that SOA works. Pulier co-authored a book about SOA, which is highly regarded.


In addition to authoring a book, Eric Pulier has founded many different technology companies, including a Starbright World, which is a social networking site for chronically ill children to connect with each other and post content. He has worked alongside Al Gore and advised on both health care and technology. One project that he is interested in that marries tech and health care is genome editing.


Pulier is known for his philanthropic lifestyle as well. He uses his knowledge and passion for technology and health care and helps people all over the world. In 2010 he was an honoree at the US Doctors for Africa event for bringing technology to Africa to help health care needs there. His ACE Foundation is working on using technology to bring clean drinking water to everyone and also sponsors contests for humanitarian technology endeavors.


A passion for technology and health care, with a background in English and classes at MIT, Eric Pulier sincerely believes in bettering the world with technological advances. His passions have earned him multiple businesses as well as the ability to aid other technology start ups and to help aid in health care needs around the globe.

Todd Lubar’s Transformation Impact in the Real Estate Industry

Todd Lubar currently serves as the President at TDL Global Ventures, LLC, and also the Senior Vice President for Legendary Investments. He started his real estate ventures after clearing his studies from Syracuse University with a Speech Communication B.A.. Currently, he lives in Bethesda Maryland with his family. Over the course of his career, Todd has helped the Maryland Legacy Financial office to expand into a large production unit value at $ 100 million annually.

Todd had always been fascinated with the trends in the real estate industry as well as the desire to assist others. This made him earn a loan originator position at Crestar Mortgage Corporation acquiring valuable experience in mortgage banking making him an expert in the sector. Over time, he partnered with several insurance agents, CPAs, real estate agent, and financial planners who became part of his excellent referral base and have taught him everything he knows.

In 1999, Todd Lubar decided to acquire the equity position with Legacy Financial Group. The position increased his lending abilities to outside investors as well as lend with the freedom of direct mortgage banks. In 2002, he established Legendary Properties, LLC, a private development organization. This company expedited rapid progression of purchasing, selling rehabilitating and profiting on more than 200 transactions comprising of single family dwellings to 20 unit multi-family properties. Legendary Properties assisted Todd in fostering relationships with the appropriate stakeholders involved in the construction of timely quality products.

In 2003, Todd launched Charter Funding, a subordinate of First Magnus Financial Corporation which is the world’s largest privately held mortgage corporation. This connection aided Todd in expanding his businesses since he had access to some wealth programs and products.

In an article on Hackronym, after Todd had observed the market trends in the real estate industry for nearly 12 years, he gauged a niche of underserved customers. This prompted him to form Legendary Financial LLC a subsidiary of Legendary Properties, LLC. The new business venture also offered commercial lending to both individuals and corporations. This is because Lubar combined the company’s assets liquidity and his funds to assist those borrowers that would be disregarded by the conventional lenders.

In 2007 and 2008, the mortgage market faced great transformations; hence, Todd decided to venture in other lines of business. One of these firms included commercial demolition which awarded Todd numerous large contracts from the biggest general contractors in the US. Additionally, he also was involved in Automotive Scrap Metal business that evolved into a public traded company. More details can be found on LinkedIn.

Cameron Clokie, the Canadian Orthopest

Dr. Cameron Clokie, a Canadian professor of Oral and Maxillofacial Surgery, has done uncountable research in his field of specialty worth recognition in the entire globe. The dental surgeon, scientist, and a business person has a Doctor of Dental Surgery and a Ph.D. from McGill University. He has worked tirelessly on developing technologies to be used in the regeneration of bone with a high level of success reported on He currently works at the University of Toronto as a teacher and a researcher.

Peter Russel, a banker, in his mid-30s lost his jaw to tumor he developed in 2003. Dr. Cameron Clokie solved his problem by forcing the jaw bone to grow by seven centimeters. After performing the successful surgical operation for four hours at Toronto General Hospital and Mount Sinai Hospital, Cameron Clokie made a comparison to a patient, Janine McFarlane, who had an almost similar problem but went through the traditional conventional operation procedures on He noted that Janine McFarlane, who was operated for 19 hours, had complications later being hospitalized for a fortnight and she could not walk for a month. In contrast, Peter Russel, who is ten years older than McFarlane, had just some slight scars hospitalized for two days and was back to the full swing of life in just two weeks.

Explaining what was behind his discovery at, Dr. Clokie narrated that he worked on Russel by modeling a gel into the jaw shape. The gap then replaced the model, and blood vessels grew over it. At high temperatures, like that of the body, the gel model dissolved slowly as it triggered cells to grow into bone. The gel is composed of morphogenetic protein, BMP, got by grinding cadaver’s leg bones though some countries like China have made other discoveries of producing it. Dr. Clokie is working on means of producing the BMP from goat milk using some genetically manipulated embryos. This is in a bid to cut down the costs involved. Molly Shoichet, Chair in Tissue Engineering, appreciated the innovation when Dr. Clokie presented it at U of T Conference.